In a study of 60 female patients suffering from papulopustular rosacea, half were treated with a hydrophilic cream containing 2% polyphenone (green tea extract) and half to vehicle cream. All women had visible signs of papules and pustules, 20 had erythema, and 17 had telangiectasia.

The women randomised to the green tea extract cream had a 70% improvement in rosacea compared with women in the vehicle cream group. (63rd Annual Meeting of the American College of Dermatology, Poster 19).