Green tea extract shrinks skin cancer tumours
Scottish researchers have developed a new delivery method for epigallocatechin gallate, an active compound from green tea, which is capable of directly targeting skin cancer cells and shrinking tumours. The researchers encapsulated the green tea extract in vesicles that also carried transferrin, a plasma protein that transports iron in the blood. Receptors for transferrin are found in large amounts in many cancers. In laboratory tests, carried out on two different types of skin cancer, nearly two-thirds of the tumours that the vesicles were delivered to either shrank or disappeared within one month, furthermore, there was no damage to normal tissues. (Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration. Nanomedicine (Lond). 2012 Aug 14. [Epub ahead of print]).