Taking Polyphenon E, a compound containing tea polyphenols including epigallocatechin-3-gallate (EGCG), can improve serum levels of prostate cancer markers in men suffering from the condition. Twenty-six men with scheduled for radical prostatectomy were given daily doses of Polyphenon E in the time leading up to their surgery. They showed a significant reduction in serum levels of prostate-specific antigen (PSA) and other inflammatory markers. Liver function tests also decreased. (Tea polyphenols decrease serum levels of prostate-specific antigen, hepatocyte growth factor, and vascular endothelial growth factor in prostate cancer patients and inhibit production of hepatocyte growth factor and vascular endothelial growth factor in vitro. Cancer Prev Res (Phila Pa). 2009 Jul;2(7):673-82).

Polyphenon E is also currently the subject of a Phase II trial to estimate its efficacy in the treatment of chronic lymphocytic leukemia (CLL). Phase I trials found that it was well tolerated by CLL patients and decreases in lymphocyte count and/or lymphadenopathy were observed in the majority of patients. (Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. J Clin Oncol. 2009 Aug 10;27(23):3808-14).

Eating mushrooms and drinking green tea have a joint effect on decreasing women’s risk of breast cancer according to a case-control study of 1,009 Chinese women. (Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women. Int J Cancer. 2009 Mar 15;124(6):1404-8).