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Gallotannin, a substance found in green tea, is up to 1000 times more powerful than comparable existing medicines in preventing brain damage after stroke. It is the overactivation of a normal DNA repair system (the PARP/PARG system), that causes cells to die after stroke. The PARP/PARG system is activated by the release of cell-damaging oxygen radicals (oxidative stress), and when cells become overexcited by various toxins. Gallotannin acts by blocking the PARP/PARG system and is 100 times more effective than antioxidants at neutralising oxidative stress. It is also effective at blocking brain cell death from chemicals that normally overexcite the cells. The researchers also found comparable results from Nobotanin B, derived from the Brazilian glory bush (Proceedings of the National Academy of Sciences 2001;98:12227). In a separate study carried out in Japan over a ten-year period, consumption of 3 or more cups of green tea a day was shown to reduce the risk of recurrence of breast cancer (Cancer Lett. 2001, 167,175-82).