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A group of Chinese authors has compared the effects of all major non-pharmacological interventions for fatigue in cancer patients, using a network meta-analysis of 182 studies comprising 18,491 participants. They found that different interventions had their own sets of advantages for addressing cancer-related fatigue, and that therapies ranked differently depending on which symptom scale was used. Acupuncture ranked best according to Treatment of Cancer Quality of Life Questionnaire, while qigong ranked at the top for the Brief Fatigue Inventory and Profile of Mood States Fatigue Subscale. Comprehensive analysis of the results indicated that multimodal therapy, cognitive behavioral therapy and qigong were the optimum selections for reducing cancer-related fatigue.

Nonpharmacological Interventions for Cancer-Related Fatigue: A Systematic Review and Bayesian Network Meta-Analysis. Worldviews Evid Based Nurs. 2019 Apr;16(2):102-110