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A Chinese study has shown that men who drink at least 1 cup of green tea per week for 6 months have a reduced risk of cancer of the colon, rectum or pancreas (Int. J. Cancer 1997, 70, 255-258). Research at the Karolinska Institute in Stockholm, Sweden has shown that a compound found in green tea can inhibit angiogenesis in mice, the process in which blood vessel growth is stimulated. The finding suggests that the compound may be useful in fighting malignant tumors, which must form new blood vessels in order to grow. Drs. Yihai Cao and Renhai Cao report that green tea, and one of its components, epigallocatechin-3-gallate (EGCG), significantly prevents the growth of new blood vessels in animals. The researchers conclude that long-term consumption of 2 to 3 cups of green tea might inhibit angiogenesis, an effect that may be beneficial in the prevention of cancers as well as other angiogenesis-dependent diseases, such as diabetic retinopathy - an eye disease that is a common cause of blindness. The researchers warn that where angiogenesis is important, as in pregnancy or in patients with healing wounds, people should not drink large amounts of tea. (Nature 1999;398:381-382). Another study has shown that drinkers of one or more cups of black tea a day are 40% less likely to suffer a heart attack than non-drinkers, whilst coffee seems to have no significant effect on heart attack risk (American Journal of Epidemiology 1999;149:162-167). A case-control study of more than 1,200 Canadian men led by researchers at the University of Toronto and recently published in the International Journal of Cancer, investigated the association of prostate cancer with consumption of alcoholic and other beverages, including tea, coffee and cola. Of the beverages studied, only tea consumption (of more than two cups per day) was associated with a decrease in risk of prostate cancer.