Sixty-one Cases of Angina Pectoris Due to Coronary Heart Disease Treated by External Use of the Paste of Nitrum and Realgar Powder On Zhiyang (GV9)

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JTCM-1110

JTCM December 2002 71/44
Liu Xin et al

(Archive subscribers please click on 'find out more' to see abstract. The full article is not available online and must be bought as a photocopy delivered by post).

Sixty-One Cases of Angina Pectoris due to Coronary Heart Disease Treated by External Use of the Paste of Nitrum and Realgar Powder on Zhiyang (GV9)

Liu Xin et al

The authors treated 91 cases of angina pectoris due to coronary heart disease, using Xiao Shi Xiong Huang San (Nitrum and Realgar Powder) in 61 cases, and nitroglycerine paste in 30 cases as a control. In each case the paste was applied to Zhiyang DU-9 daily for 10 days. The treatment group and the control group were similar in terms of age, sex and disease duration. Xiao Shi Xiong Huang San (Nitrum and Realgar powder) consists of Xiao Shi (Nitrum), Xiong Huang (Realgar) and Bing Pian (Borneol) in the ratio of 5:1:1. This is ground into a powder and then made into a paste using beeswax and sesame oil. For both the treatment group and the control group, examinations of blood, urine and faeces were carried out as well as cardiac, hepatic and renal function tests. Changes in symptoms, tongue and pulse picture, time, frequency and duration of angina attack (and causative factors), dosage of nitroglycerine, ECG readings and cholesterol levels were all monitored. For the treatment group, treatment was markedly effective in 19 cases, effective in a further 31 cases (total effective rate 82%) and ineffective in 11 cases (18%). In the control group, treatment was markedly effective in 7 cases, effective in 7 (total effective rate 53.4%), and ineffective in 16 cases (46.6%). Xiao Shi Xiong Huang San (Nitrum and Realgar Powder) is a prescription described in the Collected Medical Writing in the Dunhuang Caves, and is a first aid prescription for treating acute cardiac pain. The authors conclude that applying it topically to Zhiyang DU-9 gives significant clinical benefit.

JTCM December 2002

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